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Anti-aging medicines
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Short description:
RED WINE EXTRACT
These organic compounds have been found to beneficiary influence of many age related illneses in red wine drinkers by up to 40%. If you want to have all health benefits of red wine without alcohol consumption you should take red wine dry powder. Each Red Wine capsul contains 200 mg extract of red wine that is correspondent to 2-3 glasses of red wine Capsules do not contain alcohol!
Packing: 30 capsules, 200 mg red wine extract
Dosage: 1-2capsules a day
Description:
Resveratrol - Natural Anti-Aging Elixir
or the past 40 years, it has been virtually a dogma of Western medicine that a diet high in saturated fat and cholesterol, and/or a high blood cholesterol level, is the primary cause of heart disease.
Atherosclerosis: Heart Disease Dogma
The high blood-cholesterol so typical of Western peoples is alleged to cause atherosclerotic plaques to develop over a lifetime, eventually plugging up heart arteries and leading to death by heart attack i.e. myocardial infarction (MI) or coronary thrombosis. The so-called fatty/cholesterol plaque that can block arteries is called atheroma; the gradual development of atheroma in heart arteries is referred to as coronary atherogenesis; and the chief culprit in the process of atherogenesis is alleged to be cholesterol/saturated fat. More recent refinements of the atherogenesis dogma implicate high LDL cholesterol and/or low HDLL cholesterol as the chief culprits in atherogenesis.
Thrombi vs. Atheroma
Yet there is a mass of evidence dating back 40 years that clearly points to atheroma/atherogenesis as being secondary phenomena in the 20th-century epidemic of heart-attacks. In a 1984 review article summing up the case against atheroma as the primary cause of infarction, Wayne Martin noted that Keely and Higginson in 1957 reported widespread atheroma among the Bantus of Africa, even though they seemed to be free from heart-attacks. The researchers suggested that thrombi (abnormal blood clots) rather than atheroma may be the major cause of MI. In 1959 Gore et al. found the same degree of atheroma in Japan and in the United States, despite widely different infarction rates.
They, like Keeley and Higginson, said that it was high time more concern should be given to the danger of thrombi, with less concern about atheroma. Strong et al. are continuing a study comparing men in New Orleans, USA, with men in Tokyo, Japan. The atheroma characteristics are very little different between the two groups; but in New Orleans the death rate from MI is very high, while among the Tokyo men it is much lower. In 1980 Sinclair noted that in Jamaica, where there is severe atheroma (caused presumably by coconut oil in the diet), atheroma does not seem to cause coronary thrombosis. He stated that thrombosis, and not atheroma, is the major causal factor of myocardial infarction.
There is now abundant evidence that although man worldwide is afflicted with atheroma, many populations in Africa and Asia seem to co-exist with atheroma without being afflicted with heart-attacks.
The French Paradox
Grapes and wine contain a natural antidote to MI and cancer, scientists report. This discovery could help explain the so-called “French paradox’ - the lower rates of heart disease and cancer in nations such as France, Italy, Spain.
Platelet Aggregation and not Atheroma - main cause of MI
In a classic 1992 article about the French paradox for heart disease, Renaud and de Lorgeril present evidence that dietary fat and blood cholesterol are not primary MI villains, at least among the French. They note that the annual mortality rate per 100,000 population from coronary heart disease (CHD) is 78 in Toulouse, France, and 105 in Lille, France (for men), compared to 182 in Stanford, USA, 348 in Belfast, UK, and 380 in Glasgow, UK. Yet the saturated fat intake is about the same for these groups - 15% of the total calories. The mean serum cholesterol for men is notably lower in Stanford (209 mg%) than in France (230 in Toulouse, 252 in Lille), while Belfast (232) and Glasgow (244) levels are similar to France; yet all three have much higher MI mortality rates than France.
Renaud and de Lorgeril note that stepwise multivariate analysis shows that in the 17 countries that reported wine consumption, wine was the only foodstuff in addition to dairy fat that correlated significantly with mortality. Wine had a negative correlation, indicating a protective effect. They then present evidence that it is not through inhibitory effects on atherosclerotic lesions (atheroma) that wine provides MI protection, but rather through a decrease in the tendency of platelets to pathologically aggregate and plug up heart arteries. They compared farmers from Var, Southern France (low in CHD mortality), with farmers from south-west Scotland for platelet-aggregation tendencies. Platelet aggregation was strikingly lower in Var. Secondary aggregation to ADP, the test that undergoes the greatest decrease with alcohol, was 55% lower in Var than in Scotland, whereas mean levels of HDL cholesterol (allegedly MI-protective) were very similar (69 mg/dl in Girvan, Scotland, 66 mg/dl in Stranraer, Scotland, and 63 mg/dl in Var). Consumption of alcohol was greatest in Var (45g per day vs. 20g per day in Scotland), mostly in the form of wine.
Resveratrol
Researcher David Goldberg rhetorically asked, “Does red wine contain a biological component that is present only in limited amounts in a typical diet?” Indeed it does: resveratrol. This trihydroxystilbene is synthesized by grapes, being present in the canes, leaves and the skin of the berries. Other than peanuts, no other human-consumed foodstuff contains significant amounts. The resveratrol story does not begin with its recent discovery in wine. It actually started in the early 1980s among Japanese scientific re-searchers. Reporting in 1982, Arichi et al. noted that the dried roots of Polygonum cuspidatum have been used in traditional Japanese and Chinese medicine in a product called Kojo-kon, used to treat a wide range of afflictions, including fungal diseases of the heart, liver, and blood vessels. Resveratrol and its glycoside, polycoside polydatin have been shown to be the primary active ingredients of Kojo-kon.
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